Dongosolo la ma cell a mammalian cell expression limagwiritsa ntchito ma cell a mammalian monga HEK293 ndi CHO ndipo amathandizira kusinthidwa pambuyo pomasulira, kuphatikiza kupindika ndi glycosylation yovuta, zomwe zimapangitsa kuti mapuloteni omwe amafanana kwambiri ndi anzawo achilengedwe potengera ntchito.Chifukwa cha mwayi wapaderawu, mawonekedwe a ma cell a mammalian amatenga gawo lofunikira pakuzindikirika kwa majini, kapangidwe ka mapuloteni ndi kafukufuku wantchito, komanso kakulidwe ka mankhwala opangira ma genetic.Komabe, kachitidwe kamakono ka ma cell a mammalian ali ndi zoletsa zina, monga nthawi yayitali yosinthira komanso mtengo wokwera wopanga.