Anti-Human Her2 Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
Human epidermal growth factor receptor 2 (HER2), yomwe imadziwikanso kuti ErbB2, NEU, ndi CD340, ndi mtundu wa I membrane glycoprotein ndipo ndi wa banja la epidermal growth factor (EGF).Mapuloteni a HER2 sangathe kumanga zinthu zakukula chifukwa chosowa kwa ligand yomanga domain yake komanso yodziletsa yokha.Komabe, HER2 imapanga heterodimer ndi mamembala ena a m'banja la EGF receptor omwe amamangidwa ndi ligand, motero amakhazikika kumangiriza kwa ligand ndikuwonjezera kutsegulira kwa kinase-mediated ya mamolekyu akumunsi.HER2 imagwira ntchito yofunika kwambiri pakukula, kufalikira kwa maselo ndi kusiyanitsa.HER2 jini yanenedwa kuti ikugwirizana ndi zilonda zam'mimba komanso kusazindikira bwino kwa khansa zambiri, kuphatikizapo chifuwa, prostate, ovarian, khansa ya m'mapapo ndi zina zotero.
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 14-2 ~ 15-6 15-6 ~ 2-10 |
| Chiyero | > 95%, yotsimikiziridwa ndi SDS-PAGE |
| Kupanga kwa Buffer | PBS, pH7.4. |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| Iye 2 | Chithunzi cha AB0078-1 | 14-2 |
| AB0078-2 | 15-6 | |
| Mtengo wa AB0078-3 | 2-10 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Krawczyk N, ndi al.(2009) Mkhalidwe wa HER2 pama cell chotupa omwe amafalitsidwa mosalekeza pambuyo pa chithandizo cha adjuvant akhoza kusiyana ndi momwe HER2 ali ndi chotupa choyambirira.Anticancer Res.29(10): 4019-24.
