Anti-munthu CHI3L1 Antibody, munthu Monoclonal

Zina zambiri
Chitinase-3-like protein 1 (CHI3L1) ndi heparin-binding glycoprotein yomwe mawu ake amagwirizanitsidwa ndi kusamuka kwa mitsempha yosalala ya minofu.CHI3L1 imawonetsedwa pazikhalidwe za postconfluent nodular VSMC komanso pamilingo yotsika m'zikhalidwe zomwe zikuchulukirachulukira.CHI3L1 ndi lectin yoletsa minofu, yomwe imamangiriza chitin komanso membala wa banja la glycosyl hydrolase 18. Mosiyana ndi zizindikiro zina zambiri za monocyto / macrophage, mawu ake salipo mu monocytes ndipo amalimbikitsidwa kwambiri pamapeto a kusiyana kwa macrophage aumunthu.Magulu okwera a CHI3L1 amalumikizidwa ndi zovuta zomwe zikuwonetsa kuchuluka kwa minofu yolumikizana, monga rheum atoid, nyamakazi, osteoarthritis, scleroderma, ndi cirrhosis ya chiwindi, koma amapangidwa mu cartilage kuchokera kwa opereka akale kapena odwala osteoarthritis.CHI3L1 imasonyezedwa modabwitsa mu hippocampus ya anthu omwe ali ndi schizophrenia ndipo akhoza kutenga nawo mbali pazochitika zosiyanasiyana za chilengedwe zomwe akuti zimawonjezera chiopsezo cha schizophrenia.