Anti- human IGFBP-1 Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
IGFBP1, yomwe imadziwikanso kuti IGFBP-1 ndi insulin-monga kukula factor-binding protein 1, ndi membala wa insulin-monga kukula factor-binding protein family.Mapuloteni omanga a IGF (IGFBPs) ndi mapuloteni a 24 mpaka 45 kDa.Ma IGFBP onse asanu ndi limodzi amagawana 50% homology ndipo ali ndi ma affinities omangirira a IGF-I ndi IGF-II pamlingo womwewo monga momwe ma ligand ali ndi IGF-IR.Mapuloteni omangirira a IGF amatalikitsa theka la moyo wa ma IGF ndipo awonetsedwa kuti amalepheretsa kapena kulimbikitsa kukula kwa ma IGF pa chikhalidwe cha cell.Amasintha kuyanjana kwa ma IGF ndi ma cell receptors awo.IGFBP1 ili ndi IGFBP domain ndi thyroglobulin type-I domain.Imamanga zinthu zonse za insulin-monga kukula (IGFs) I ndi II ndikuzungulira mu plasma.Kumangirira kwa puloteni iyi kumatalikitsa theka la moyo wa ma IGF ndikusintha kuyanjana kwawo ndi ma cell cell receptors.
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| Chiyero | > 95% malinga ndi SDS-PAGE. |
| Kupanga kwa Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kufananiza Kwampikisano
| Bioantibody | Mlandu Wopezeka ndi Matenda | Zonse | |
| Zabwino | Zoipa | ||
| Zabwino | 35 | 0 | 35 |
| Zoipa | 1 | 87 | 88 |
| Zonse | 36 | 87 | 123 |
| Mwatsatanetsatane | 100% | ||
| Kumverera | 97% | ||
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Rutanen EM .Insulin-monga kukula kwa chinthu chomanga mapuloteni 1: US 1996.
2.Harman, S, Mitchell, et al.Miyezo ya Serum ya Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, ndi Prostate-Specific Antigen monga Predictors of Clinical Prostate Cancer[J].Journal of Clinical Endocrinology & Metabolism, 2000.
