Anti-anthu MMP-3 Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
Matrix metallopeptidase 3 (yofupikitsidwa ngati MMP3) amadziwikanso kuti stromelysin 1 ndi progelatinase.MMP3 ndi membala wa banja la matrix metalloproteinase (MMP) omwe mamembala ake akukhudzidwa ndi kuwonongeka kwa matrix a extracellular muzochitika zachibadwa za thupi, monga kukula kwa embryonic, kubereka, kukonzanso minofu, ndi njira za matenda kuphatikizapo nyamakazi ndi metastasis.Monga endopeptidase yodalira zinki, MMP3 imagwira ntchito zake makamaka mu matrix owonjezera.Puloteniyi imayendetsedwa ndi ma inhibitors awiri akuluakulu: alpha2-macroglobulin ndi ma tissue inhibitors a metalloproteases (TIMPs).MMP3 imakhala ndi gawo lalikulu pakuwononga kolajeni mitundu II, III, IV, IX, ndi X, proteoglycans, fibronectin, laminin, ndi elastin.Komanso, MMP3 imatha kuyambitsa ma MMP ena monga MMP1, MMP7, ndi MMP9, kupangitsa kuti MMP3 ikhale yofunikira pakukonzanso minofu.Kuwonongeka kwa ma MMP kwakhudzidwa ndi matenda ambiri kuphatikiza nyamakazi, zilonda zam'mimba, encephalomyelitis, ndi khansa.Ma Synthetic kapena Natural inhibitors a MMPs amabweretsa kuletsa kwa metastasis, pomwe kuwongolera kwa ma MMP kumapangitsa kuwonjezereka kwa maselo a khansa.
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4 |
| Chiyero | > 95%, yotsimikiziridwa ndi SDS-PAGE |
| Kupanga kwa Buffer | PBS, pH7.4. |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kufananiza Kwampikisano
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| MMP-3 | AB0025-1 | 11G11-6 |
| AB0025-2 | 8A3-9 | |
| AB0025-3 | 5B9-4 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Yamanaka H , Matsuda Y , Tanaka M , et al.Serum matrix metalloproteinase 3 monga cholosera cha kuchuluka kwa kuwonongeka kwa mafupa m'miyezi isanu ndi umodzi pambuyo poyeza, mwa odwala omwe ali ndi nyamakazi yoyambirira [J].Matenda a Nyamakazi & Rheumatism, 2000, 43 (4): 852-858.
2.Hattori Y, Kida D, Kaneko A.Miyezo yachibadwa ya serum matrix metalloproteinase-3 ingagwiritsidwe ntchito kulosera zachikhululukiro chachipatala ndi ntchito yabwino ya thupi kwa odwala omwe ali ndi nyamakazi ya nyamakazi [J].Clinical Rheumatology, 2018.
