Anti-anthu PGI Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
Pepsinogen I, omwe amatsogolera pepsin, amapangidwa ndi chapamimba mucosa ndikumasulidwa mu lumen ya m'mimba ndi kuzungulira kwa zotumphukira.Pepsinogen imakhala ndi unyolo umodzi wa polypeptide wa 375 amino acid wokhala ndi kulemera kwapakati kwa 42 kD.PG I (isoenzyme 1-5) imatulutsidwa makamaka ndi maselo akuluakulu a mucosa ya fundic, pamene PG II (isoenzyme 6-7) imatulutsidwa ndi pyloric glands ndi proximal duodenal mucosa.
Precursor imawonetsa kuchuluka kwa ma cell am'mimba komanso ma cell a glandular, ndipo imayang'anira gastric atrophy mosalunjika.Amakhalanso okhazikika modabwitsa chifukwa amagwira ntchito zawo pansi pa zovuta zomwe zimapezeka m'chigayo.The atrophy of the corpus mucosa imabweretsa kutsika kwa pepsinogen I ndipo chifukwa chake kutulutsidwa kwake kochepa mu seramu.Seramu pepsinogen I imasonyeza ntchito ndi mayendedwe a chapamimba mucosa.
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 1C1-3 ~ 1G7-3 1E3-1 ~ 1G7-3 |
| Chiyero | > 95%, yotsimikiziridwa ndi SDS-PAGE |
| Kupanga kwa Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kusanthula Kuyerekeza
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| PGI | AB0005-1 | 1C1-3 |
| AB0005-2 | 1E3-1 | |
| AB0005-3 | 1G7-3 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Sipponen P , Ranta P , Helske T , et al.Miyezo ya seramu ya amidated gastrin-17 ndi pepsinogen I mu atrophic gastritis: kafukufuku wowongolera milandu.[J].Scandinavia Journal of Gastroenterology, 2002, 37 (7): 785-791.
2.Mangla JC , Schenk EA , Desbaillets L , et al.Pepsin secretion, pepsinogen, ndi gastrin mu esophagus ya Barrett.Makhalidwe azachipatala ndi morphological[J].Gastroenterology, 1976, 70 (5 PT.1): 669-676.
