Zina zambiri
Preeclampsia ndi vuto lalikulu lomwe limakhalapo chifukwa chokhala ndi pakati, lomwe limachitika pakati pa 3 - 5% ya oyembekezera, ndipo ndi chimodzi mwazomwe zimayambitsa matenda obadwa nawo komanso imfa padziko lonse lapansi.
Preeclampsia imatanthauzidwa ngati kuyambika kwatsopano kwa matenda oopsa komanso proteinuria pambuyo pa milungu 20 ya bere.Mawonetseredwe azachipatala a preeclampsia ndi njira yotsatiridwa ya matendawa imatha kukhala yosiyana kwambiri, zomwe zimapangitsa kulosera, kuzindikira komanso kuyesa kukula kwa matenda kukhala kovuta.
Zinthu za Angiogenic (sFlt-1 ndi PlGF) zimatsimikiziridwa kuti zimakhudza kwambiri pathogenesis ya preeclampsia ndipo kuchuluka kwawo mu seramu ya amayi kumasinthidwa ngakhale matendawa asanayambike kuwapangitsa kukhala chida cholosera komanso kuthandizira kuzindikira preeclampsia.
Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 1E4-6 ~ 2A6-4 2A6-4 ~ 1E4-6 |
Chiyero | > 95% malinga ndi SDS-PAGE. |
Kupanga kwa Buffer | PBS, pH7.4. |
Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
sFlt-1 | AB0029-1 | 1E4-6 |
AB0029-2 | 2A6-4 | |
AB0029-3 | 2H1-5 | |
AB0029-4 | 4D9-10 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
1. Stepan H , Geide A , Faber R .Kusungunuka kwa fms-ngati tyrosine kinase 1.[J].N Engl J Med, 2004, 351(21):2241-2242.
2.Kleinrouweler CE , Wiegerinck M , Ris-Stalpers C , et al.Kulondola kwa kufalikira kwa kukula kwa placenta, vascular endothelial growth factor, soluble fms-monga tyrosine kinase 1 ndi endoglin yosungunuka pakulosera kwa pre-eclampsia: kuwunika mwadongosolo ndi kusanthula meta.[J].Bjog An International Journal of Obstetrics & Gynaecology, 2012, 119(7):778-787.