Anti-Human RBP4 Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
Retinol-binding protein 4 (RBP4) ndiyomwe imanyamula retinol (yomwe imadziwikanso kuti vitamini A), ndipo imayang'anira kusintha kwa retinol yosakhazikika komanso yosasungunuka m'madzi amadzimadzi kukhala okhazikika komanso osungunuka m'madzi a m'magazi kudzera mu kugwirizana kwawo kolimba.Monga membala wa lipocalin superfamily, RBP4 yomwe ili ndi β-barrel yopangidwa ndi mbiya yodziwika bwino imatulutsidwa kuchokera ku chiwindi, ndipo imatulutsa retinol kuchokera ku masitolo a chiwindi kupita ku ziwalo zozungulira.Mu madzi a m'magazi, RBP4-retinol complex imagwirizana ndi transthyretin (TTR), ndipo kumanga kumeneku n'kofunika kwambiri kuti tipewe kutuluka kwa RBP4 kudzera mu impso glomeruli.RBP4 yowonetsedwa kuchokera ku ectopic source imapereka bwino retinol m'maso, ndipo kusowa kwake kumakhudza kwambiri masomphenya ausiku.Posachedwapa, RBP4 monga adipokine, imapezeka kuti ikuwonetsedwa mu minofu ya adipose ndipo imagwirizana ndi kunenepa kwambiri, insulin resistance (IR) ndi mtundu wa 2 shuga (T2DM).
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Chiyero | > 95% malinga ndi SDS-PAGE. |
| Kupanga kwa Buffer | PBS, pH7.4. |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kufananiza Kwampikisano
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| Mtengo wa RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Aiwei YB , Vijayalakshmi V , Bodles AM , et al.Retinol kumanga mapuloteni 4 mwa anthu: ubale ndi insulin kukana, kutupa, ndi kuyankha kwa pioglitazone.[J].J Clin Endocrinol Metab (7): 2590-2597.
2.Haider DG , Karin S , Gerhard P , et al.Serum retinol-binding protein 4 imachepetsedwa pambuyo pa kuwonda kwa anthu onenepa kwambiri.[J].Journal of Clinical Endocrinology & Metabolism (3): 1168-71.
