Zina zambiri
Mahomoni ogonana omwe amamanga globulin (SHBG) ndi glycoprotein pafupifupi 80-100 kDa;ali ndi kuyanjana kwakukulu kwa 17 beta-hydroxysteroid mahomoni monga testosterone ndi estradiol.Mtengo wa SHBG
Kuchuluka kwa madzi a m'magazi kumayendetsedwa ndi, mwa zina, androgen / estrogen balance, mahomoni a chithokomiro, insulini ndi zakudya.Ndilo puloteni yofunika kwambiri yonyamula ma estrogens ndi ma androgens m'magazi am'mphepete.Kukhazikika kwa SHBG ndiye chinthu chachikulu chomwe chimayang'anira kugawa kwawo pakati pa maiko omwe ali ndi mapuloteni komanso aulere.Kukhazikika kwa plasma SHBG ndi
okhudzidwa ndi matenda osiyanasiyana osiyanasiyana, makhalidwe apamwamba omwe amapezeka mu hyperthyroidism, hypogonadism, androgen insensitivity ndi hepatic cirrhosis mwa amuna.Kutsika kochepa kumapezeka mu myxoedema, hyperprolactinemia ndi ma syndromes a zochita zambiri za androgen.Kuyeza kwa SHBG ndikothandiza pakuwunika zovuta za kagayidwe ka androgen ndikuzindikiritsa azimayi omwe ali ndi hirsutism omwe amatha kuyankha pamankhwala a estrogen.
Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
Chiyero | > 95%, yotsimikiziridwa ndi SDS-PAGE |
Kupanga kwa Buffer | PBS, pH7.4. |
Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
SHBG | AB0030-1 | 3A10-5 |
AB0030-2 | 3E10-1 | |
AB0030-3 | 3D8-2 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
1. Selby C. Hormone yogonana yomanga globulin: chiyambi, ntchito ndi kufunikira kwachipatala.Ann Clin Biochem 1990; 27:532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Chithandizo chachipatala cha mahomoni ogonana omwe amamanga muyeso wa globulin.Horm Res 1996; 45 (3-5): 148-155.