Anti-munthu TIMP1 Antibody, Mouse Monoclonal
Zambiri zamalonda
Zina zambiri
TIMP metallopeptidase inhibitor 1, yomwe imadziwikanso kuti TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibitors of the metalloproteinase matrix amakhudzidwa ndi kuwonongeka kwa matrix a extracellular.TIMP-1/TIMP1 imapezeka mu minyewa ya mwana wakhanda komanso wamkulu.Zokwera kwambiri zimapezeka m'mafupa, mapapo, ovary ndi chiberekero.Zimaphatikizana ndi metalloproteinase ndipo zimazimitsa mosasinthika pomangiriza ku cofactor yake ya zinc.TIMP-1/TIMP1 imayimira erythropoiesis in vitro;koma, mosiyana ndi IL-3, ndizosiyana ndi zamoyo, zomwe zimalimbikitsa kukula ndi kusiyana kwa anthu okhawo ndi murine erythroid progenitors.Kuphatikiza pa ntchito yake yoletsa motsutsana ndi ma MMP ambiri odziwika, mapuloteni amatha kulimbikitsa kukula kwa maselo m'magulu osiyanasiyana a maselo, komanso akhoza kukhala ndi anti-apoptotic ntchito.Kulemba kwa jini yopangira mapuloteniwa kumatheka kwambiri poyankha ma cytokines ndi mahomoni ambiri.Kuphatikiza apo, mawu ochokera ku ma chromosomes ena osagwira ntchito a X akuwonetsa kuti kusagwira ntchito kwa jiniku ndi polymorphic mwa akazi aumunthu.jini yoyikirayi ili mkati mwa intron 6 ya synapsin I jini ndipo imalembedwa mbali ina.Zimaphatikizana ndi metalloproteinase ndipo zimazimitsa mosasinthika pomangiriza ku cofactor yake ya zinc.TIMP-1/TIMP1 Imadziwika kuti ikuchita pa MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 ndi MMP-16.
Katundu
| Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 1D5-5 ~ 3G11-6 1D12-2 ~ 1G3-7 |
| Chiyero | > 95% malinga ndi SDS-PAGE. |
| Kupanga kwa Buffer | PBS, pH7.4. |
| Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Kufananiza Kwampikisano
Kuitanitsa Zambiri
| Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
| TIMP1 | AB0034-1 | 1D5-5 |
| AB0034-2 | 1D12-2 | |
| AB0034-3 | 1G3-7 | |
| AB0034-4 | 3G11-6 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
Zolemba
1.Barylski M , Kowalczyk E , Szadkowska I , et al.[Tissue inhibitor of metalloproteinases[J].Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.
2.Hayakawa T , Yamashita K , Tanzawa K , et al.Ntchito yopititsa patsogolo kukula kwa minofu inhibitor ya metalloproteinases-1 (TIMP-1) yamitundu yambiri yamaselo A zotheka kukula kwatsopano mu seramu[J].FEBS Letters, 1992, 298.
3.Haider DG , Karin S , Gerhard P , et al.Serum retinol-binding protein 4 imachepetsedwa pambuyo pa kuwonda kwa anthu onenepa kwambiri.[J].Journal of Clinical Endocrinology & Metabolism (3): 1168-71.
