Zina zambiri
S100B ndi puloteni yomanga calcium, yomwe imatulutsidwa kuchokera ku astrocyte.Ndi puloteni yaying'ono ya dimeric cytosolic (21 kDa) yomwe imakhala ndi unyolo wa ββ kapena αβ.S100B imakhudzidwa ndi machitidwe osiyanasiyana oyendetsera ma intracellular ndi extracellular.
M'zaka khumi zapitazi, S100B yakhala ikuwoneka ngati chizindikiro chamagazi-brain barrier (BBB) kuwonongeka ndi kuvulala kwa CNS.Miyezo yokwezeka ya S100B ikuwonetsa bwino kukhalapo kwa matenda a neuropathological kuphatikiza kuvulala kowopsa kwa mutu ndi matenda a neurodegenerative.Miyezo yodziwika bwino ya S100B imapatula matenda akulu a CNS.Serum S100B yanenedwanso kuti ndi yothandiza pozindikira msanga ma metastases a melanoma ndi zovuta zaubongo chifukwa chovulala mutu, opaleshoni yamtima, ndi sitiroko yowopsa.
Awiri Malangizo | CLIA (Kujambula-Kuzindikira): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
Chiyero | > 95% malinga ndi SDS-PAGE. |
Kupanga kwa Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Kusungirako | Sungani pansi pazikhalidwe zosabala pa -20 ℃ mpaka -80 ℃ mukalandira. Ndibwino kuti aliquot mapuloteniwo muchuluke kakang'ono kuti asungidwe bwino. |
Dzina lazogulitsa | Mphaka.Ayi | Clone ID |
s100 ndi | Chithunzi cha AB0061-1 | 5H2-3 |
Chithunzi cha AB0061-2 | 22G7-5 | |
Chithunzi cha AB0061-3 | 21A6-1 |
Chidziwitso: Bioantibody imatha makonda malinga ndi zosowa zanu.
1. Ostendorp T , Leclerc E , Galicet A , et al.Kuzindikira kwamapangidwe ndi magwiridwe antchito mu RAGE activation ndi multimeric S100B[J].The EMBO Journal, 2007, 26 (16): 3868-3878.
2. R, D, Rothoerl, et al.Miyezo yapamwamba ya seramu ya S100B kwa odwala ovulala popanda kuvulala mutu.[J].Neurosurgery, 2001.