Anti-anthu IL6, Mouse Monoclonal

Zina zambiri
Interleukin-6 (IL-6) ndi multifunctional α-helical cytokine yomwe imayang'anira kukula kwa maselo ndi kusiyanitsa kwa mitundu yosiyanasiyana ya minyewa, yomwe imadziwika makamaka chifukwa cha gawo lake pakuyankha kwa chitetezo chamthupi komanso machitidwe owopsa a gawo.Mapuloteni a IL-6 amapangidwa ndi mitundu yosiyanasiyana ya maselo kuphatikiza ma T cell ndi macrophages monga phosphorylated komanso mosiyanasiyana glycosylated molecule.Imachita zinthu kudzera mu cholandilira chake cha heterodimeric chopangidwa ndi IL-6R chomwe chilibe tyrosine / kinase domain ndipo chimamanga IL-6 ndi kuyanjana kochepa, komanso kuwonetsa ponseponse glycoprotein 130 (gp130) yomwe imamanga IL-6.IL-6R yovuta yokhala ndi kuyanjana kwakukulu ndipo motero imatulutsa ma sign.IL-6 imakhudzidwanso ndi hematopoiesis, mafupa a metabolism, ndi kukula kwa khansa, ndipo yatanthauzidwa ngati gawo lofunikira pakuwongolera kusintha kuchokera ku chibadwa kupita ku chitetezo chokwanira.